Dynamic PET Image Denoising With Deep Learning-Based Joint Filtering
نویسندگان
چکیده
Dynamic positron emission tomography (PET) imaging usually suffers from high statistical noise due to low counts of the short frames. This study aims improve image quality frames by utilizing information other modality. We develop a deep learning-based joint filtering framework for simultaneously incorporating longer acquisition PET and high-resolution magnetic resonance (MR) images into The network inputs are noisy corresponding MR while outputs linear coefficients spatially variant representation model. composite all dynamic is used as training label in each sample, it down-sampled 1/10th input. L1-norm combined with two gradient-based regularizations constitute loss function during training. Ten realistic PET/MR phantoms based on BrainWeb pre-training eleven clinical subjects Alzheimer's Disease Neuroimaging Initiative further fine-tuning. Simulation results show that proposed method can reduce preserving details achieve quantitative enhancements compared Gaussian, guided filter, convolutional neural trained mean squared error. perform better than others terms activity standard deviation. All indicate great potential denoising.
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ژورنال
عنوان ژورنال: IEEE Access
سال: 2021
ISSN: ['2169-3536']
DOI: https://doi.org/10.1109/access.2021.3064926